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Tienilic Acid

CAS No. 40180-04-9

Tienilic Acid ( Ticrynafen; ANP 3624 )

Catalog No. M28066 CAS No. 40180-04-9

Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 35 Get Quote
10MG 65 Get Quote
25MG 132 Get Quote
50MG 196 Get Quote
100MG 291 Get Quote
200MG 435 Get Quote
500MG 698 Get Quote
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Biological Information

  • Product Name
    Tienilic Acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity.
  • Description
    Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity.(In Vivo):In female and male Sprague-Dawley rats, Tienilic Acid decreased blood pressure and serum uric acid at 30 mg/kg. Tienilic acid decreased slightly hemoglobin and increased S-GPT at 120 and 480 mg/kg. Tienilic Acid significantly increase the liver weight and serum magnesium concentration in male rats, while the liver weight of female rats increased only slightly. Tienilic Acid also induced unicellular necrosis of small groups of liver cells.
  • Synonyms
    Ticrynafen; ANP 3624
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40180-04-9
  • Formula Weight
    331.2
  • Molecular Formula
    C13H8Cl2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)COc1ccc(C(=O)c2cccs2)c(Cl)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chan FC, et al. 3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancer. J Med Chem. 1996 Aug 16;39(17):3319-23.
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